IMPORTANT NOTICE REGARDING OUR SERVICE DURING THE COVID-19 PANDEMIC
Covid-19 Service Update

At Medix Pharmacy, the health and safety of our customers and staff is our highest priority. Due to the worldwide Covid-19 pandemic affecting us all, there have been some changes within our industry in general, and in our company specifically, that we want to make our customers aware of.

Call Center

Our current call center hours of operation are 6AM – 9PM every day, seven days per week. If you are experiencing increased hold times or are calling outside of these hours, please leave us a message or send us an email and we will get back to you as soon as we can. Due to increased demand on telephone networks worldwide, you may experience some intermittent connection problems. If this happens our agents will call you back.

Shipping

We are currently seeing delays in our regular shipping times. Our normal shipping time averages 1 - 2 weeks. Shipments may now take an additional 2 – 4 weeks or more to arrive, depending on the source country of your order.

Please note that these times are averages and individual shipping times will vary. We highly recommend that you place your order at least 2 – 4 weeks or more ahead of your normal reorder time to avoid running out of your medication.

These are industry-wide delays and are mainly occurring due to disruptions in local postal delivery in the countries where our customers live. They are temporary, and we thank the shipping and delivery personnel who are working hard for all of us during this global crisis.

Please Note: As these types of shipping delays are not within our direct control, we are temporarily adjusting our regular Shipping Guarantee from 30 days to 60 days. We will provide updates as the situation changes.

Our Commitment

If you have any questions about any changes in our service please do not hesitate to contact us. Our staff are working tirelessly to ensure the timely fulfillment and delivery of all orders. The health of our customers and staff is our highest priority and we remain committed to providing service at the highest level.

We thank you for your support in these challenging times.


Management and Staff
Medix Pharmacy

Daliresp
(Roflumilast)

Prescription Settings Edit

Brand Name Choices

Daliresp 250mcg
Daliresp 250mcg

Marketed as Daxas in United Kingdom

Roflumilast

Manufactured by Merck Sharp & Dohme Ltd

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

Parallel Import

Daliresp 500mcg
Daliresp 500mcg

Marketed as Daxas in United Kingdom

Roflumilast

Manufactured by Merck Sharp & Dohme Ltd

Product of United Kingdom

Dispensed by a licensed pharmacy in the United Kingdom

Prescription Required

Parallel Import

Daliresp 500mcg
Daliresp 500mcg

Marketed as Daxas in Canada

Roflumilast

Manufactured by AstraZeneca Canada Inc

Product of Canada

Dispensed by an approved Canadian pharmacy partner

Prescription Required

More Brand Name Choices

Generic Choices

No generic medication is available for Daliresp (Roflumilast)

What Daliresp is and what it is used for

Daxas contains the active substance roflumilast, which is an anti-inflammatory medicine called phosphodiesterase-4 inhibitor. Roflumilast reduces the activity of phosphodiesterase-4, a protein occurring naturally in body cells. When the activity of this protein is reduced, there is less inflammation in the lungs. This helps to stop narrowing of airways occurring in chronic obstructive pulmonary disease (COPD). Thus Daxas eases breathing problems. Daxas is used for maintenance treatment of severe COPD in adults who in the past had frequent worsening of their COPD symptoms (so-called exacerbations) and who have chronic bronchitis. COPD is a chronic disease of the lungs that results in tightening of the airways (obstruction) and swelling and irritation of the walls of the small air passages (inflammation). This leads to symptoms such as coughing, wheezing, chest tightness or difficulty in breathing. Daxas is to be used in addition to bronchodilators.

How to take Daliresp

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
• For the first 28 days
•the recommended starting dose is one 250 micrograms tablet once daily.
•The starting dose is a low dose used to help your body get used to the medicine before you start taking the full dose. At this low dose you will not get the full effect from the medicine – therefore it is important that you move on to the full dose (called a ‘maintenance dose’) after 28 days.
• After 28 days
•the recommended maintenance dose is one 500 micrograms tablet once daily. Swallow the tablet with some water. You may take this medicine with or without food. Take the tablet at the same time every day. You may need to take Daxas for several weeks to achieve its beneficial effect. If you take more Daxas than you should If you have taken more tablets than you should, you may experience the following symptoms: headache, nausea, diarrhoea, dizziness, throbbing of your heart, light-headedness, clamminess and low blood pressure. Tell your doctor or pharmacist straight away. If possible take your medicine and this leaflet with you. If you forget to take Daxas If you forget to take a tablet at the usual time, take the tablet as soon as you remember on the same day. If on one day you have forgotten to take a tablet of Daxas, just carry on the next day with the next tablet as usual. Continue taking your medicine at the usual times. Do not take a double dose to make up for a forgotten dose. 4 If you stop taking Daxas It is important to continue taking Daxas for as long as prescribed by your doctor, even when you have no symptoms, in order to maintain control of your lung function. If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. You may experience diarrhoea, nausea, stomach ache or headache during the first weeks of treatment with Daxas. Talk to your doctor if these side effects do not resolve within the first weeks of treatment. Some side effects could be serious. In clinical studies and post-marketing experience, rare instances of suicidal thinking and behaviour (including suicide) were reported. Please notify your doctor immediately of any suicidal thoughts you may have. You may also experience sleeplessness (common), anxiety (uncommon), nervousness (rare), panic attack (rare) or depressive mood (rare). In uncommon cases allergic reactions may occur. Allergic reactions may affect the skin and in rare cases cause swelling of the eyelids, face, lips and tongue, possibly leading to difficulties in breathing and/or a drop in blood pressure and accelerated heartbeat. In case of an allergic reaction, stop taking Daxas and contact your doctor immediately, or go immediately to the emergency department in the nearest hospital. Take all your medicines and this leaflet with you and provide full information of your current medications.

Other side effects include the following:

Common side effects (may affect up to 1 in 10 people)
•diarrhoea, nausea, stomach ache
•weight decrease, decreased appetite
•headache

Uncommon side effects (may affect up to 1 in 100 people)
•trembling, sensation of spinning head (vertigo), dizziness
•sensation of rapid or irregular heartbeat (palpitations)
•gastritis, vomiting
•reflux of stomach acid to the gullet (acid regurgitations), indigestion
•rash
•muscle pain, muscle weakness or cramps
•back pain
•feeling of weakness or tiredness, feeling unwell.

Rare side effects (may affect up to 1 in 1,000 people)
•male breast enlargement
•decreased sense of taste
•respiratory tract infections (excluding pneumonia)
•bloody stools, constipation
•elevation of liver or muscle enzymes (seen in blood tests) 5
•wheals (urticaria).

Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly (see details below). By reporting side effects you can help provide more information on the safety of this medicine. United Kingdom Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Ireland HPRA Pharmacovigilance Earlsfort Terrace IRL
•Dublin 2 Tel: +353 1 6764971 Fax: +353 1 6762517 Website: www.hpra.ie e-mail: [email protected] Malta ADR Reporting Website: www.medicinesauthority.gov.mt/adrportal

How to Store Daliresp

Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. The expiry date refers to the last day of that month. This medicine does not require any special storage conditions. Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

Fast Shipping

2 to 3 weeks on average

The average shipping time is 2 weeks in North America and 4 weeks internationally. We offer free shipping on all orders shipped to North America. Shipping is a flat rate of $20.00 for all other countries.

Price Match Guarantee

If you have been prescribed medication by your doctor and cannot afford the high price at your local pharmacy, Medix Pharmacy is the solution for you. All orders are backed with a price match and satisfaction guarantee.

About Medix Pharmacy

Medix Pharmacy is a fully licensed pharmacy in the United Kingdom who provides competitive pricing on brand and generic medications with international shipping.

We are regulated by a number of executive government agencies in the United Kingdom including the Medicines and Healthcare products Regulatory Agency and the GPhC to ensure we offer our customers the highest level of service and peace of mind knowing that the medicines that you receive are safe, effective and authentic.

Drug prices for Daliresp vary throughout the world with the highest prices generally in the United States. Patients can save significantly on their prescriptions drugs when purchasing them from a licensed pharmacy in the United Kingdom and other countries such as Canada, Australia, and New Zealand.

If you are unable to find your prescribed medicine on our website, please fill out the form below and we will confirm pricing and availability within 1 business day. You may also call us at 1-866-500-6633 and one of our patient care representatives will be happy to assist you.